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Updated: Dec 16, 2025

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Microvascular Decompression: Salient Surgical Principles and Technical Nuances
Published on: July 5, 2011
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DSAEK Centration and Interface Folds: Surgical Management.
Kunal Gadhvi1, Luca Pagano1, Nardine Menassa1
1St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom; and.
Cornea
|July 4, 2020
Summary
A new technique precisely centers Descemet stripping automated endothelial keratoplasty (DSAEK) grafts, resolving interface folds. This atraumatic method improves graft alignment for better outcomes.
Area of Science:
- Ophthalmology
- Corneal Surgery
- Transplantation
Background:
- Descemet stripping automated endothelial keratoplasty (DSAEK) is a common procedure for endothelial dysfunction.
- Graft centering and preventing interface folds are critical for successful DSAEK outcomes.
- Current techniques may involve excessive manipulation, risking endothelial damage.
Purpose of the Study:
- To present a novel, atraumatic technique for centering DSAEK lamellar grafts.
- To demonstrate a method for resolving interface folds during DSAEK surgery.
Main Methods:
- A novel technique using a STC-6 needle passed obliquely through the anterior cornea.
- The needle engages and progresses the lenticule along the posterior corneal surface.
- Air injection facilitates graft manipulation and centration without undue endothelial contact.
Main Results:
- Successful centration of the DSAEK graft was achieved.
- Macroscopic interface folds were effectively resolved.
- The technique proved to be atraumatic and reproducible.
Conclusions:
- A novel, atraumatic, and reproducible method for DSAEK graft centration is described.
- This technique effectively addresses interface folds, potentially improving surgical outcomes.
- The described method offers a valuable alternative for DSAEK graft alignment.

