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Updated: Dec 16, 2025

Methodology for Sputum Induction and Laboratory Processing
Published on: December 17, 2017
Saliva-controlled sputum culture (SSC) - A high value diagnostic tool for deep pulmonary infections
1Department of Cell Biology and Physiology, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel.
Abstract:
A major obstacle to prompt diagnosis of fungal pulmonary infections is that deep sputum samples are scarce, yet are frequently rejected if they contain saliva. We show that including saliva controls unfailingly distinguishes oropharyngeal flora from pulmonary fungi, thus preserving valuable samples for analysis, expediting diagnoses and improving patient care.
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