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A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
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Diabetes and COVID-19: Global and regional perspectives

In-Kyung Jeong1, Kun Ho Yoon2, Moon Kyu Lee3

  • 1Department of Endocrinology and Metabolism, Kyung Hee University School of Medicine, Kyung Hee University Hospital at Gangdong, Seoul, Republic of Korea.

Diabetes Research and Clinical Practice
|July 6, 2020
PubMed

Insights

Diabetes significantly increases the risk of severe outcomes and death from coronavirus disease-2019 (COVID-19). Patients with diabetes require specific precautions and careful management during the COVID-19 pandemic.

Area of Science:

  • Infectious Diseases
  • Endocrinology
  • Public Health

Background:

  • The COVID-19 pandemic, caused by SARS-CoV-2, has resulted in a global health crisis.
  • Diabetes is identified as a major risk factor for severe COVID-19 outcomes.
  • Diabetic patients face increased vulnerability due to hyperglycemia, impaired immunity, and comorbidities.

Purpose of the Study:

  • To review current knowledge on COVID-19 epidemiology and virology.
  • To examine the impact of diabetes on COVID-19 severity and mortality.
  • To discuss COVID-19 treatment and diabetes management standards during the pandemic.

Main Methods:

  • Literature review of COVID-19 and diabetes research.
  • Analysis of epidemiological data and clinical outcomes.
  • Synthesis of information on treatment strategies and care standards.

Main Results:

  • COVID-19 severity and mortality rates are significantly higher in diabetic patients.
  • Hyperglycemia, immune dysfunction, and comorbidities exacerbate COVID-19 in diabetics.
  • ACE2 receptor interaction highlights the need for caution with angiotensin-directed medications.

Conclusions:

  • Diabetic patients are at high risk for severe COVID-19 and require heightened precautions.
  • Effective management of diabetes is crucial during the pandemic.
  • Further research is needed on specific treatment and care protocols for diabetic COVID-19 patients.

Keywords:
Angiotensin-converting enzyme 2Coronavirus disease-2019 (COVID-19)Diabetes mellitusSevere acute respiratory syndrome coronavirus-2

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