Related Experiment Video
Updated: Dec 16, 2025
Control of Cell Adhesion using Hydrogel Patterning Techniques for Applications in Traction Force Microscopy
Published on: January 29, 2022
Gradient Photothermal Field for Precisely Directing Cell Sheet Detachment
Jiange Jing1, Shuangshuang Chen2, Qinghua Lu1,2
1School of Chemistry and Chemical Engineering, The State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, Shanghai, 200240, China.
Abstract:
Due to the remaining intact intercellular interactions, cell sheets play increasing roles in biomedical fields. Recently, spatiotemporal control of cell sheets has become an urgent requirement in the context of precise surgery. Here, the development of a gradient photothermal biointerface for precisely directing cell sheet detachment through quantitatively regulating the dissociation rate of collagen is reported. This novel and facile method shows great potential for application in precise regenerative medicine.
