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Updated: Dec 15, 2025

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children

Published on: August 22, 2012

Human Ascariasis: An Updated Review.

Alexander K C Leung¹, Amy A M Leung², Alex H C Wong³

¹Department of Pediatrics, The University of Calgary, Alberta Children's Hospital, Calgary, Alberta, Canada.

Recent Patents on Inflammation & Allergy Drug Discovery

|July 7, 2020

Summary

This summary is machine-generated.

Ascariasis, a common helminthic infection affecting over 1.2 billion people, is effectively treated with anthelminthics, achieving over 95% cure rates. Long-term prevention requires improved sanitation and health education to combat re-infection in endemic areas.

Keywords:

Albendazole Ascaris lumbricoides Löeffler syndrome biliary obstruction intestinal obstruction mebendazole pancreatitis pyrantel pamoate

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Mass Isolation and In Vitro Cultivation of Intramolluscan Stages of the Human Blood Fluke Schistosoma Mansoni

Mass Isolation and In Vitro Cultivation of Intramolluscan Stages of the Human Blood Fluke Schistosoma Mansoni

Published on: January 14, 2018

Area of Science:

Infectious Diseases
Public Health
Tropical Medicine

Background:

Ascariasis, caused by Ascaris lumbricoides, is the most prevalent helminthic infection globally, impacting over 1.2 billion individuals.
High endemicity is observed in tropical and subtropical regions, disproportionately affecting children under five due to factors like poverty and poor sanitation.

Purpose of the Study:

To provide an updated overview of the evaluation, diagnosis, and treatment of ascariasis.
To review current management strategies and recent advancements in ascariasis control.

Main Methods:

A comprehensive literature search was conducted using PubMed and patent databases for studies on ascariasis published within the last decade.
The search included meta-analyses, clinical trials, observational studies, and reviews, focusing on English-language publications.

Main Results:

Transmission occurs via ingestion of embryonated eggs from fecal-contaminated sources; diagnosis is confirmed by microscopic fecal examination.
While anthelminthic treatment (albendazole, mebendazole, or pyrantel pamoate for pregnant women) yields high cure rates (>95%), re-infection is common in endemic areas.
Complications range from asymptomatic infection to severe conditions like intestinal obstruction and malnutrition.

Conclusions:

Anthelminthic treatment is crucial for all patients, including asymptomatic individuals, to prevent complications.
Long-term prevention strategies must focus on health education, personal hygiene, improved sanitation, and proper waste disposal.
Mass deworming programs should be considered in highly prevalent regions to reduce the burden of ascariasis.