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Mobile Phone Technologies in the Management of Ischemic Heart Disease, Heart Failure, and Hypertension: Systematic
Praveen Indraratna1,2, Daniel Tardo3,4, Jennifer Yu1,2
1Department of Cardiology, Prince of Wales Hospital, Sydney, Australia.
Insights
Mobile phone interventions (MPIs) can help manage cardiovascular diseases (CVD). Studies show MPIs reduce hospitalizations for heart failure and lower blood pressure in hypertension patients.
Area of Science:
- Cardiology
- Digital Health
- Public Health
Background:
- Cardiovascular disease (CVD) is a leading global cause of mortality.
- Mobile phones are widespread, offering new avenues for chronic disease management.
- Smartphone apps, telemonitoring, and SMS are emerging tools for managing conditions like heart failure and hypertension.
Purpose of the Study:
- To systematically review randomized control trials (RCTs) on mobile phone interventions (MPIs) for chronic CVD management.
- To assess the impact of MPIs on mortality, hospitalizations, blood pressure (BP), and body mass index (BMI).
Main Methods:
- A systematic review of seven electronic databases was conducted from January 2000 to June 2019.
- Twenty-six RCTs involving 6713 patients were identified; 12 were included in a meta-analysis.
- Meta-analysis used standard techniques with odds ratios for dichotomous variables and a random effect model.
Main Results:
- Mobile phone interventions (MPIs) significantly reduced hospitalizations in heart failure patients (OR 0.77, P=.03).
- MPIs were associated with a significant decrease in systolic blood pressure for hypertension patients (mean difference -4.3 mm Hg, P=.02).
- A total of 26 RCTs with 6713 patients were analyzed.
Conclusions:
- Mobile phone interventions show promise as a valuable addition to managing chronic cardiovascular diseases.
- Further research may solidify the role of digital health tools in cardiovascular care.
- MPIs offer a novel approach to support cardiac rehabilitation and chronic disease management.
Background:
Cardiovascular disease (CVD) remains the leading cause of death worldwide. Mobile phones have become ubiquitous in most developed societies. Smartphone apps, telemonitoring, and clinician-driven SMS allow for novel opportunities and methods in managing chronic CVD, such as ischemic heart disease, heart failure, and hypertension, and in the conduct and support of cardiac rehabilitation.
Objective:
A systematic review was conducted using seven electronic databases, identifying all relevant randomized control trials (RCTs) featuring a mobile phone intervention (MPI) used in the management of chronic CVD. Outcomes assessed included mortality, hospitalizations, blood pressure (BP), and BMI.
Methods:
Electronic data searches were performed using seven databases from January 2000 to June 2019. Relevant articles were reviewed and analyzed. Meta-analysis was performed using standard techniques. The odds ratio (OR) was used as a summary statistic for dichotomous variables. A random effect model was used.
Results:
A total of 26 RCTs including 6713 patients were identified and are described in this review, and 12 RCTs were included in the meta-analysis. In patients with heart failure, MPIs were associated with a significantly lower rate of hospitalizations (244/792, 30.8% vs 287/803, 35.7%; n=1595; OR 0.77, 95% CI 0.62 to 0.97; P=.03; I2=0%). In patients with hypertension, patients exposed to MPIs had a significantly lower systolic BP (mean difference 4.3 mm Hg; 95% CI -7.8 to -0.78 mm Hg; n=2023; P=.02).
Conclusions:
The available data suggest that MPIs may have a role as a valuable adjunct in the management of chronic CVD.
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