A Rare Cause of Type II Neovascularization: Unilateral Retinal Pigment Epithelium Dysgenesis

Unilateral retinal pigment epithelium dysgenesis (URPED) is a very rare clinical condition first described in 2002. Fundus examination and imaging findings are almost pathognomonic and can facilitate diagnosis of this uncommon disease. In this article, we present a 32-year-old patient who developed type II neovascularization (NV) as a complication of URPED. After 6 months of monthly intravitreal bevacizumab injection, visual acuity increased from 20/32 to 20/20 but optic coherence tomography findings were partially improved. The aim of this report is to highlight URPED and secondary type II NV, the pathogenesis and prognosis of which are unknown but which cause visual loss especially in the younger population.