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[Keratomycosis caused by Candida albicans].
E Arocker-Mettinger1, V Huber-Spitzy, R Haddad
12. Universitäts-Augenklinik.
Klinische Monatsblatter Fur Augenheilkunde
|August 1, 1988
Summary
A corneal infection caused by Candida albicans occurred in a patient with multiple myeloma after a corneal transplant. Prompt combination therapy, including antifungals and anterior chamber medication, successfully resolved the mycotic keratitis.
Area of Science:
- Ophthalmology
- Mycology
- Infectious Diseases
Background:
- Corneal transplantation (penetrating keratoplasty) can be complicated by opportunistic infections.
- Multiple myeloma is an immunosuppressive condition that may predispose patients to fungal infections.
Observation:
- A 78-year-old female developed mycotic keratitis in her right eye three months post-penetrating keratoplasty.
- Candida albicans was identified in the aqueous humor during intraocular surgery.
Findings:
- The patient was treated with systemic ketoconazole and intravenous miconazole.
- Topical miconazole eye drops and intracameral amphotericin B were administered.
- This combination antifungal therapy led to the resolution of the corneal infection.
Implications:
- Aggressive and multi-modal antifungal treatment is crucial for managing post-keratoplasty mycotic keratitis.
- Patients with underlying immunosuppressive conditions require vigilant monitoring for ocular infections.
- Candida albicans can cause severe keratitis following corneal transplantation, necessitating prompt diagnosis and treatment.