Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Positional hypoxaemia following post-traumatic pulmonary insufficiency.

J D Katz, P G Barash

    Canadian Anaesthetists' Society Journal
    |May 1, 1977
    PubMed
    Summary

    Body position significantly impacts lung function in unilateral lung disease. Placing the diseased lung downward worsens gas exchange, while upward positioning improves it, especially with positive end-expiratory pressure (PEEP).

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Humoral and T-cell responses to SARS-CoV-2 vaccination in multiple sclerosis patients treated with ocrelizumab.

    Multiple sclerosis and related disorders·2022
    Same author

    Pain does not suffer misprision: an inquiry into the presence and absence that is pain.

    Medical humanities·2013
    Same author

    Issues of concern for the aging anesthesiologist.

    Anesthesia and analgesia·2001
    Same author

    An aldol approach to the synthesis of the EF fragment of spongistatin 1.

    Organic letters·2001
    Same author

    Pulmonary artery catheter under the microscope.

    Critical care medicine·2001
    Same author

    A case of Balamuthia mandrillaris meningoencephalitis.

    Archives of neurology·2000

    Area of Science:

    • Pulmonary Medicine
    • Respiratory Physiology
    • Critical Care

    Background:

    • Understanding how body positioning affects ventilation is crucial for patients with unilateral lung disease.
    • Positive pressure ventilation, with and without positive end-expiratory pressure (PEEP), is commonly used in managing respiratory compromise.

    Observation:

    • Pulmonary dynamics were assessed in supine, right, and left decubitus positions.
    • Gas exchange was evaluated under zero end-expiratory pressure (ZEEP) and 5 cm H2O PEEP.
    • Changes in arterial oxygenation (PaO2) and venous admixture were measured.

    Findings:

    • When the diseased lung was dependent, PaO2 decreased and venous admixture increased compared to the supine position.
    • These negative effects were more pronounced under ZEEP than PEEP.
    • Conversely, with the diseased lung non-dependent, PaO2 increased and venous admixture decreased, particularly with PEEP.

    Implications:

    • Body position can cause significant, clinically relevant changes in pulmonary gas exchange.
    • Careful patient positioning is essential in managing unilateral lung disease to optimize oxygenation.
    • The use of PEEP may mitigate some adverse effects of dependent positioning on gas exchange.

    Related Experiment Videos