Related Experiment Video
Updated: Dec 15, 2025

Translational Orthotopic Models of Glioblastoma Multiforme
Published on: February 17, 2023
Meningioangiomatosis: Clinical, Imaging, and Histopathologic Characteristics
Mina S Makary1, Peter Kobalka2, Pierre Giglio3
1Department of Radiology, Division of Neuroradiology, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States.
Abstract:
Meningioangiomatosis is a rare benign lesion involving the central nervous system. Radiographic appearance can be highly variable which makes pre-operative diagnosis difficult. In this report, we describe meningioangiomatosis in a previously healthy 17-year-old woman who presented with seizures and continued headache and dizziness. This patient presented with a predominately calcified lesion on imaging and eventually underwent near total resection. Meningioangiomatosis is difficult to preoperatively identify, but is an important consideration as prognosis with surgical resection is typically good.
Insights
Meningioangiomatosis is a rare central nervous system lesion. Early diagnosis and surgical resection of this benign condition offer a good prognosis.
Area of Science:
- Neuroscience
- Neuropathology
- Neuroradiology
Background:
- Meningioangiomatosis is a rare, benign central nervous system (CNS) lesion.
- Its variable radiographic appearance complicates preoperative diagnosis.
- Understanding this condition is crucial for effective patient management.
Observation:
- We report a case of meningioangiomatosis in a 17-year-old female presenting with seizures, headache, and dizziness.
- Imaging revealed a predominantly calcified lesion.
- The patient underwent near-total surgical resection.
Findings:
- Meningioangiomatosis presents diagnostic challenges due to its diverse imaging characteristics.
- Calcification can be a prominent feature in some meningioangiomatosis cases.
- Surgical intervention is a key treatment modality.
Implications:
- Accurate preoperative diagnosis of meningioangiomatosis remains difficult.
- Despite diagnostic challenges, surgical resection is associated with favorable outcomes.
- Increased awareness of meningioangiomatosis aids in timely and appropriate treatment.

