Related Experiment Video
Updated: Dec 15, 2025

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging
Published on: September 12, 2011
Birmingham and Beyond
1Virginia Commonwealth University, School of Medicine, Richmond, VA, USA.
Abstract:
Nick Martin was a doctoral student of mine at the University of Birmingham in the mid 1970s. In this review, I discuss two of Nick's earliest and most seminal contributions to the field of behavior genetics. First, Martin and Eaves' (1977) extension of the model-fitting approach to multivariate data, which laid the theoretical groundwork for a generation of multivariate behavior genetic studies. Second, the Martin et al.'s (1978) manuscript on the power of the classical twin design, which showed that thousands of twin pairs would be required in order to reliably estimate components of variance, and has served as impetus for the formation of large-scale twin registries across the world. I discuss these contributions against the historical backdrop of a time when we and others were struggling with the challenge of figuring out how to incorporate gene-by-environment interaction, gene-environment correlation, mate selection and cultural transmission into more complex genetic models of human behavior.
Related Concept Videos
Brick Masonry
For thicker walls, multiple wythes are bonded together using...
Brick Sizes
Modular bricks are the most common type and are sized to include the mortar joint, which is essential for...
Bones of the Lower Limb: Femur and Patella
Bones of the Upper Limb: Humerus
Masonry Paving
Southern Blot
Denatured DNA fragments must be transferred onto a carrier membrane from the gel to make it accessible to a probe - a small ssDNA fragment complementary to the target DNA...

