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Updated: Dec 15, 2025
Isolated Lung Perfusion System in the Rabbit Model
Published on: July 15, 2021
The feasibility and effectiveness of thoracoscopic transdiaphragmatic approach for lung biopsy in rabbits. A
Monica Carolina Nery Wittmaack1, Felipe Farias Pereira da Câmara Barros2, Paloma do Espírito Santo Silva3
1MSc, Fellow PhD degree, Postgraduate Program in Science, Department of Veterinary Surgery, School of Agrarian Sciences and Veterinary Medicine (FCAV), Universidade Estadual Paulista (UNESP), Jaboticabal-SP, Brazil. Conception and design of the study; acquisition, analysis and interpretation of data; technical procedures.
Purpose:
To assess the feasibility of thoracoscopic transdiaphragmatic approach for biopsy of all lung lobes and to determine the optimal intercostal space (ICS) for biopsy of each lung lobe.
Methods:
Ten rabbits were positioned in dorsal recumbency. Total thoracoscopy lung biopsy was made combined transdiaphragmatic approach and right ICS approaches. A camera port was made in the transdiaphragmatic approach and the instrument port was made of ICS 7 and ICS 9. A pre tied loop ligature was placed to performed a caudal lung lobe biopsy and to simulate biopsies of the others lung lobes.
Results:
Biopsy of the cranial aspect of the right caudal lung lobe was performed at ICS 9. Simulated biopsy of the accessory lung lobe was performed at ICS 9. Simulated lung biopsy of the right cranial and middle lung lobes was performed at ICS 7. The caudal and dorsal aspect of the right caudal lung lobe was not visualized by telescope at transdiaphragmatic approach, and biopsy was not performed.
Conclusions:
Thoracoscopic transdiaphragmatic approach for lung lobes biopsies was a feasible technique, except for the caudal aspect of the right caudal lung lobe. An ideal intercostal port for biopsy of each right lung lobe was determined.
