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Macrocyclic Peptide-Mediated Blockade of the CD47-SIRPα Interaction as a Potential Cancer Immunotherapy

Daisuke Hazama1, Yizhen Yin2, Yoji Murata3

  • 1Division of Molecular and Cellular Signaling, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan; Division of Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.

Cell Chemical Biology
|July 9, 2020
PubMed

Keywords:
CD47SIRPαcancerimmunotherapyinnate immune checkpointmacrocyclic peptidemacrophagephagocytosis

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