Related Experiment Video
Updated: Dec 15, 2025
Middle Cerebral Artery Occlusion Allowing Reperfusion via Common Carotid Artery Repair in Mice
Published on: January 23, 2019
Predictive value on diffusion weighted imaging scores for basilar artery occlusion after endovascular treatment
Can Wan1, Guangliang Wu2, Xing Jin1
1Second Clinical Medical School, 47879Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Insights
The Renard diffusion weighted imaging score may predict functional outcomes in basilar artery occlusion patients after endovascular treatment. Early intervention and collateral flow also influence patient recovery.
Area of Science:
- Neurology
- Radiology
- Interventional Neuroradiology
Background:
- Basilar artery occlusion (BAO) is a severe condition requiring prompt endovascular treatment.
- Predicting functional outcomes in BAO patients is crucial for guiding treatment decisions and managing expectations.
Purpose of the Study:
- To evaluate the predictive accuracy of three diffusion-weighted imaging (DWI) scoring systems for functional outcomes in BAO patients post-endovascular treatment.
- To identify independent predictors of favorable outcomes.
Main Methods:
- Retrospective analysis of 88 BAO patients treated between January 2010 and June 2019.
- Assessment of early ischemic changes using DWI pc-ASPECTS Score, Renard DWI Score, and DWI Brainstem Score.
- Modified Rankin Scale (mRS) used to define favorable (0-2) and unfavorable (3-6) outcomes at three months.
Main Results:
- Time to puncture within 12 hours, presence of PCoA or PICA-SCA collateral flow, and NIHSS score ≤15 were independently associated with favorable outcomes.
- A Renard DWI score ≤1.5 was also a significant predictor of favorable outcomes (AUC 0.63, P=0.046).
Conclusions:
- The Renard DWI score shows potential as an independent predictor of functional outcomes in BAO patients after endovascular therapy.
- Timely intervention and adequate collateral circulation are critical factors influencing patient recovery.
Purpose:
To assess the predictive value of three scoring systems based on diffusion weighted imaging in basilar artery occlusion patients after endovascular treatment.
Methods:
We analyzed clinical and radiological data of patients with basilar artery occlusion from January 2010 to June 2019, with modified Rankin Scale of 0-2 and 3-6 defined as favorable outcome and unfavorable outcome at three months. Diffusion weighted imaging posterior circulation ASPECTS Score (DWI pc-ASPECT Score), Renard diffusion weighted imaging Score, and diffusion weighted imaging Brainstem Score were used to evaluate the early ischemic changes.
Results:
There were a total of 88 basilar artery occlusion patients enrolled in the study after endovascular treatment, with 33 of them getting a favorable outcome. According to the analysis, the time from onset to puncture within 12 h (odds ratio: 4.34; 95% confidence interval: 1.55-12.16; P = 0.01), presence of collateral flow via PCoA (odds ratio: 0.31; 95%CI: 0.12-0.79; P = 0.01) or between PICA and SCA (odds ratio: 0.18; 95%CI: 0.07-0.47; P = 0.00), equal or less than 15 points on baseline NIHSS (area under the curve 0.79, 95% CI 0.69-0.89; sensitivity = 69.1%, specificity = 81.8%; P = 0.00), and equal or less than 1.5 points on diffusion weighted imaging Renard score (area under the curve 0.63, 95% CI 0.51-0.75; sensitivity = 83.6%, specificity = 39.4%; P = 0.046) were independently associated with favorable outcome.
Conclusions:
Renard diffusion weighted imaging score may be an independent predictor of functional outcome in basilar artery occlusion patients after endovascular treatment.
