Related Experiment Video

Updated: Dec 15, 2025

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
04:40

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans

Published on: August 28, 2018

15.8K

A study on the prevalence, distribution and related factors of heart valve calcification using coronary CT

Yuki Kamo1, Shinichiro Fujimoto1, Chihiro Aoshima1

  • 1Department of Cardiovascular Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.

International Journal of Cardiology. Heart & Vasculature
|July 10, 2020
PubMed

Insights

Heart valve calcification (HVC) affects nearly half of patients undergoing coronary CT angiography (CCTA). Aortic valve calcification is linked to age and coronary artery calcium score, but mitral valve calcification is only associated with age.

Area of Science:

  • Cardiovascular Imaging
  • Radiology
  • Pathology

Background:

  • Heart valve calcification (HVC) is increasingly recognized as an active atherosclerotic process.
  • Understanding the prevalence and contributing factors of HVC is crucial for cardiovascular risk assessment.

Purpose of the Study:

  • To investigate the prevalence, distribution, and associated factors of HVC in patients who underwent coronary CT angiography (CCTA).
  • To explore the relationship between HVC and coronary artery disease indicators.

Main Methods:

  • Retrospective analysis of 200 consecutive patients who underwent CCTA.
  • ECG-gated non-contrast CT was used to assess HVC prevalence and distribution in aortic and mitral valves.
  • Logistic and simple regression analyses were performed to identify associated factors.

Main Results:

  • HVC was detected in 48.0% of patients, with aortic valve calcification (AVC) being most common (92 cases).
  • Age and coronary artery calcium score (CACS) grade were significant factors associated with AVC presence.
  • Age, dyslipidemia, and statin use were associated with quantitative AVC; only age was linked to MVC presence.

Conclusions:

  • A significant association exists between the presence of AVC and CACS.
  • No significant association was found between mitral valve calcification (MVC) and CACS or coronary artery disease.
  • Neither quantitative AVC nor MVC showed a significant association with CACS or coronary artery disease.
Abstract

Keywords:
Coronary CT angiographyCoronary artery calcium scoreCoronary artery diseaseHeart valve calcification

More Related Videos

Investigating Aortic Valve Calcification via Isolation and Culture of T Lymphocytes using Feeder Cells from Irradiated Buffy Coat04:30

Investigating Aortic Valve Calcification via Isolation and Culture of T Lymphocytes using Feeder Cells from Irradiated Buffy Coat

Published on: February 4, 2021

3.6K
Author Spotlight: Advancing Cardiovascular Imaging - Introducing the Spatially Weighted Calcium Score for Early Disease Detection06:57

Author Spotlight: Advancing Cardiovascular Imaging - Introducing the Spatially Weighted Calcium Score for Early Disease Detection

Published on: September 22, 2023

1.4K

Related Concept Videos

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
269
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
177
Imaging Studies for Cardiovascular System III: X-Ray01:20

Imaging Studies for Cardiovascular System III: X-Ray

The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
397
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
760
Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

Mitral Stenosis II: Clinical features and Diagnostic Tests

Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
131
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
266