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Urodynamic Assessment of Neuronal Intranuclear Inclusion Disease
Yosuke Aiba1, Ryuji Sakakibara2, Fang-Ching Lee3
1Neurology, Internal Medicine, Sakura Medical Center, Toho University, Sakura, Japan.
Abstract:
Neuronal intranuclear inclusion disease (NIID) is a disease that causes leukoencephalopathy (dementia) and peripheral neuropathy (variable manifestation including bladder dysfunction). This is the first urodynamic report to show that bladder dysfunction in NIID is a combination of detrusor overactivity, decreased bladder sensation, large post-void residual, and neurogenic changes in the sphincter electromyogram. This report will help managing bladder dysfunction in NIID.
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