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Superior vena cava thrombosis and dilated cardiomyopathy as initial presentations of Behcet's disease

Ahmed M Elzanaty1, Mohammed T Awad1, Ashu Acharaya1

  • 1Internal Medicine Departement, University of Toledo, 3000 Arlington Avenue, Toledo, OH 43614 USA.

Thrombosis Journal
|July 11, 2020
PubMed

Insights

Behcet's disease, a rare condition causing ulcers, can initially present with serious cardiovascular issues like dilated cardiomyopathy and superior vena cava thrombosis. Early recognition is key for timely Behcet's disease diagnosis and treatment.

Area of Science:

  • Cardiology
  • Rheumatology
  • Internal Medicine

Background:

  • Behcet's disease (BD) is a rare multisystem inflammatory disorder.
  • Systemic manifestations of BD commonly include oral and genital ulcers.
  • Cardiac and venous involvement, such as dilated cardiomyopathy (DCM) and superior vena cava (SVC) thrombosis, are rare initial presentations of BD.

Observation:

  • A 32-year-old male presented with severe headaches and dyspnea.
  • The patient was diagnosed with SVC thrombosis and DCM.
  • A diagnosis of Behcet's disease was established following a thorough medical history.

Findings:

  • Cardiovascular complications, including DCM and SVC thrombosis, can be the earliest clinical signs of Behcet's disease.
  • This case highlights the diagnostic challenge posed by atypical initial presentations of BD.

Implications:

  • Early clinical recognition of Behcet's disease is crucial for managing cardiovascular manifestations.
  • Prompt diagnosis of BD can prevent severe complications associated with DCM and SVC thrombosis.
  • This case underscores the importance of considering rare systemic diseases in patients with unexplained cardiovascular and thrombotic events.
Abstract

Keywords:
Behcet’s diseaseDilated cardiomyopathySVC thrombosis

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