Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Factors Affecting the Risk of Infection

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Effect of Minimizing Light Exposure with Digital Visualization on Macular Function After Cataract Surgery in Patients with AMD: A Randomized Controlled Trial.

Journal of clinical medicine·2026

Same author

Traumatic intravitreal egg-shaped hematoma.

Eye (London, England)·2026

Same author

Multimodal imaging findings in juvenile ocular cystinosis before and after cysteamine drops.

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)·2026

Same author

Development and validation of an online extraction HPLC-HRMS method for the quantification of carbapenems in FecalSwab™ samples.

Journal of pharmaceutical and biomedical analysis·2026

Same author

Epidemiology and antimicrobial resistance patterns of Aeromonas species in Europe, 2020-2024 (AEuROMONAS).

Diagnostic microbiology and infectious disease·2026

Same author

A decade of ocular fungal infections due to Penicillium-like fungi in France (2012-2021).

Medical mycology·2026

Search research articles

Related Experiment Video

Updated: Dec 15, 2025

Establishing a Porcine Ex Vivo Cornea Model for Studying Drug Treatments against Bacterial Keratitis

Establishing a Porcine Ex Vivo Cornea Model for Studying Drug Treatments against Bacterial Keratitis

Published on: May 12, 2020

Moraxella keratitis: epidemiology and outcomes.

Gautier Hoarau¹, Lilia Merabet¹, Françoise Brignole-Baudouin^1,2

¹INSERM-DGOS CIC 1423, IHU ForeSight, CHNO des Quinze-Vingts, 28 rue de Charenton, F-75012, Paris, France.

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology

|July 11, 2020

Summary

Moraxella keratitis, a rare but sight-threatening condition, often affects patients with ocular surface issues like blepharitis. Early identification of risk factors is crucial for preventing vision loss.

Keywords:

Blepharitis Cornea Keratitis Moraxella Neurotrophic keratopathy

More Related Videos

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Author Spotlight: Establishing a Practical and Cost-Effective Protocol for Corneal Sensitivity Testing in Clinical Settings

Author Spotlight: Establishing a Practical and Cost-Effective Protocol for Corneal Sensitivity Testing in Clinical Settings

Published on: August 2, 2024

Related Experiment Videos

Last Updated: Dec 15, 2025

Establishing a Porcine Ex Vivo Cornea Model for Studying Drug Treatments against Bacterial Keratitis

Establishing a Porcine Ex Vivo Cornea Model for Studying Drug Treatments against Bacterial Keratitis

Published on: May 12, 2020

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Author Spotlight: Establishing a Practical and Cost-Effective Protocol for Corneal Sensitivity Testing in Clinical Settings

Author Spotlight: Establishing a Practical and Cost-Effective Protocol for Corneal Sensitivity Testing in Clinical Settings

Published on: August 2, 2024

Area of Science:

Ophthalmology
Infectious Diseases
Microbiology

Background:

Moraxella keratitis is an uncommon ocular infection.
Understanding its prevalence, risk factors, and outcomes is vital for clinical management.

Purpose of the Study:

To assess the prevalence, risk factors, and visual outcomes of Moraxella keratitis.
To identify prognostic factors associated with poorer visual acuity and need for adjuvant treatment.

Main Methods:

Retrospective review of 101 culture-proven Moraxella keratitis cases (Jan 2016-Dec 2018).
Microbiological identification using MALDI-TOF MS.
Analysis of patient demographics, ocular surface conditions, systemic factors, and treatment outcomes.

Main Results:

Moraxella lacunata (50%) and M. nonliquefasciens (38%) were the most common isolates.
28% had systemic predisposing factors (e.g., diabetes), 87% had ocular surface conditions (e.g., blepharitis, prior surgery).
Hypopyon and age >60 years predicted poorer visual acuity; larger infiltrate and hypoesthesia predicted need for adjuvant treatment.

Conclusions:

Moraxella keratitis, though rare in France, poses a significant threat to vision.
Identifying patients with compromised ocular surfaces, especially neurotrophic keratopathy, is key to preventing delayed healing and reducing the need for interventions like amniotic membrane transplantation.