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Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
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Right ventricular involvement in left ventricular non-compaction cardiomyopathy.
Simon F Stämpfli1,2, Alexander Gotschy3,4, Pascal Kiarostami3
1Department of Cardiology, University Heart Center Zurich, Switzerland. simon.staempfli@usz.ch.
Cardiology Journal
|July 11, 2020
Summary
Right ventricle (RV) trabeculation in left ventricular non-compaction cardiomyopathy (LVNC) can be quantified by cardiac magnetic resonance (CMR). However, increased RV trabeculation in LVNC significantly overlaps with normal individuals, preventing clear distinction.
Area of Science:
- Cardiology
- Cardiovascular Imaging
- Cardiac Morphology
Background:
- Left ventricular non-compaction cardiomyopathy (LVNC) is characterized by excessive trabeculations in the left ventricle.
- Right ventricular (RV) involvement in LVNC is recognized, but differentiating abnormal RV trabeculation from normal anatomy is challenging.
Purpose of the Study:
- To assess right ventricular (RV) morphology and function in patients with left ventricular non-compaction cardiomyopathy (LVNC).
- To evaluate the utility of cardiac magnetic resonance (CMR) and transthoracic echocardiography (TTE) in characterizing RV involvement in LVNC.
Main Methods:
- Utilized cardiac magnetic resonance (CMR) and transthoracic echocardiography (TTE) to assess RV dimensional and functional parameters.
- Introduced novel CMR parameters including RV end-diastolic (ED) trabeculated area, RV ED trabeculated volume, and RV ED non-compacted to compacted (NC/C) ratio in short axis (SAX) and four-chamber (4CH) views.
Main Results:
- Twenty patients with LVNC and 20 controls were studied. RV size and function were comparable between groups and showed good correlation between TTE and CMR.
- While RV trabeculated area, volume, and NC/C ratio were higher in LVNC, significant overlap with control values was observed.
- RV ED NC/C ratio in SAX correlated with LV ED NC/C ratio, but quantitative RV non-compaction assessment was not feasible with TTE.
Conclusions:
- Cardiac magnetic resonance (CMR) and transthoracic echocardiography (TTE) can measure right ventricle (RV) size and function in LVNC.
- CMR allows quantification of RV trabeculation, but increased trabeculation in LVNC extensively overlaps with normal individuals, hindering definitive separation.
Keywords:
cardiac magnetic resonance imagingechocardiographyleft ventricular non-compaction cardiomyopathytrabeculationMore Related Videos
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