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Oxidative Stress, Diet and Prostate Cancer
Bee Ling Tan1, Mohd Esa Norhaizan1,2,3
1Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Selangor, Malaysia.
The World Journal of Men'S Health
|July 11, 2020
Summary
Prostate cancer progression is linked to elevated reactive oxygen species (ROS). Dietary antioxidants may help prevent prostate cancer by modulating oxidative stress and inflammation.
Area of Science:
- Oncology
- Biochemistry
- Nutrition Science
Background:
- Prostate cancer is a leading cancer in men globally.
- Androgen influences prostate function and reactive oxygen species (ROS) balance.
- Elevated ROS levels are associated with prostate cancer development and progression.
Purpose of the Study:
- To review the mechanisms of oxidative stress in prostate cancer progression.
- To examine how dietary components affect inflammation, oxidative stress, and prostate cancer.
- To provide insights into dietary strategies for prostate cancer prevention.
Main Methods:
- Literature review focusing on oxidative stress, androgens, and diet in prostate cancer.
- Analysis of existing evidence on the role of dietary antioxidants.
- Synthesis of information on mechanisms linking diet, oxidative stress, and cancer.
Main Results:
- Androgen signaling impacts ROS balance in the prostate.
- Oxidative stress, indicated by elevated ROS, contributes to prostate cancer.
- Dietary components can modulate oxidative stress and inflammation, influencing cancer risk.
Conclusions:
- Understanding the mechanisms of oxidative stress is crucial for prostate cancer management.
- Dietary interventions hold potential for preventing and managing prostate cancer.
- Further research into dietary components' effects on oxidative stress is warranted.
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