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[Clinical, secretory and immunologic studies in Terrien disease]
H Gornig1, H Kohlmann, C Merrem
1Augenklinik des Bereiches Medizin der Karl-Marx-Universität Leipzig.
Klinische Monatsblatter Fur Augenheilkunde
|November 1, 1988
Summary
Terrien
Area of Science:
- Ophthalmology
- Immunology
Background:
- Terrien's disease is a rare corneal degeneration.
- Clinical signs often include inflammation.
Purpose of the Study:
- To investigate tear secretion and inflammation markers in Terrien's disease.
Main Methods:
- Radionuclide dacryography (RND) was used to assess tear secretion.
- Immunoglobulin G (IgG) levels in tear fluid were measured.
- Serum parameters were analyzed.
Main Results:
- Reduced tear secretion was observed in some patients via RND.
- Slightly elevated IgG levels in tear fluid correlated with inflammation.
- Serum levels of electrolytes and minerals were normal.
Conclusions:
- Tear hyposecretion may be present in Terrien's disease.
- Elevated IgG in tears suggests an inflammatory component.