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Updated: Dec 15, 2025

Single Cell Collection of Trophoblast Cells in Peri-implantation Stage Human Embryos
Published on: June 12, 2020
Single Cell Transcriptomes Derived from Human Cervical and Uterine Tissue during Pregnancy
Winston Koh1,2, Angela Wu3, Lolita Penland1
1Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA.
Abstract:
This work presents the workflow for generating single cell transcriptomes derived from primary human uterine and cervical tissue obtained during planned cesarean hysterectomies. In total, a catalogue of 310 single cell transcriptomes are obtained, cell types present in these biopsies are inferred, and specific genes defining each of the cellular types present in the tissue are identified. Further validation of the inferred cell identity is also demonstrated via meta-analysis of independent repositories in literature generated by bulk sequenced data of fluorescence-activated cell sorting sorted cells.
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