Related Experiment Video
Updated: Dec 15, 2025

Biological Compatibility Profile on Biomaterials for Bone Regeneration
Published on: November 16, 2018
Foreign Body Reaction to Poly-D-L-Lactic Acid Resorbable Plates Used in Craniofacial Surgery
Nicholas Cen1,2, Matthew J Davis1,2, Amjed Abu-Ghname1,2
1Division of Plastic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine.
Abstract:
Resorbable surgical materials are often used in the pediatric population to provide fixation in the growing skeleton. Although foreign body reactions to poly-D-L-lactic acid (PDLLA) plates and screws have been previously reported in other fields, to date PDLLA polymers have been well-tolerated in the setting of craniofacial surgery. The authors report a case of a previously healthy 4-month-old patient with Crouzon syndrome who underwent a frontal-orbital advancement with resorbable PDLLA plates and screws and subsequently experienced extensive foreign body reactions and wound healing complications.

