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Ophthalmic Complications in Pediatric Uveitis

Natasha Gautam Seth1, Savleen Kaur1, Sonam Yangzes1

  • 1Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Ocular Immunology and Inflammation
|July 11, 2020
PubMed

Insights

Pediatric uveitis in North India presents with significant complications. Cataract is most critical at presentation, while elevated intraocular pressure and maculopathy leading to blindness are common during follow-up.

Area of Science:

  • Ophthalmology
  • Pediatric Medicine
  • Inflammatory Eye Diseases

Background:

  • Pediatric uveitis is a significant cause of visual impairment in children.
  • Understanding complication patterns is crucial for effective management.

Purpose of the Study:

  • To investigate the spectrum of complications in pediatric uveitis patients from North India.
  • To identify common complications at presentation and during follow-up.

Main Methods:

  • Retrospective analysis of 104 children (<16 years) diagnosed with uveitis.
  • Data collected between January 2006 and March 2015.
  • Mean follow-up duration of 3.40 ± 2.34 years.

Main Results:

  • At presentation, cataract (24.00%), band-shaped keratopathy (18.29%), and glaucoma/ocular hypertension (OHT) (6.29%) were most frequent.
  • During follow-up, glaucoma/OHT (29.71%) and cataract (18.86%) were most common.
  • Maculopathy (35%) and glaucoma/OHT (20%) were leading causes of severe vision loss (visual acuity ≤3/60).

Conclusions:

  • Cataract is the primary complication at presentation in pediatric uveitis.
  • Elevated intraocular pressure is a frequent complication during follow-up, potentially treatment-related.
  • Maculopathy is the leading cause of blindness in this cohort.

Keywords:
Pediatriccomplicationsinflammationocularuveitis

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