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Updated: Dec 15, 2025

Catalytic Scavenging of Plant Reactive Oxygen Species In Vivo by Anionic Cerium Oxide Nanoparticles
Published on: August 26, 2018
Antioxidant Functionalized Nanoparticles: A Combat against Oxidative Stress.
Harsh Kumar1, Kanchan Bhardwaj2, Eugenie Nepovimova3
1School of Bioengineering & Food Technology, Shoolini University of Biotechnology and Management Sciences, Solan 173229, Himachal Pradesh, India.
Antioxidant functionalized nanoparticles offer a novel solution to combat oxidative stress, overcoming the bioavailability challenges of traditional antioxidants. This approach enhances cellular protection against reactive oxygen species (ROS) damage.
Area of Science:
- Biochemistry
- Materials Science
- Nanotechnology
Background:
- Abiotic stresses induce reactive oxygen species (ROS), causing cellular damage and diseases.
- Conventional antioxidants face bioavailability issues like poor absorption and degradation.
- Nanoparticles as antioxidants are underutilized, with limited exploration of nanomaterials.
Purpose of the Study:
- To review antioxidant functionalized nanoparticles for enhanced ROS scavenging.
- To explore the synergistic potential of natural antioxidants and biogenic nanoparticles.
- To elucidate the mechanisms of antioxidant-empowered nanoparticles against oxidative stress.
Main Methods:
- Literature review on antioxidant functionalized nanoparticles.
- Analysis of antioxidant properties of secondary metabolites from biological sources (algae, bacteria, fungi, lichens, plants).
- Investigation of biogenic nanoparticles for enhanced antioxidant delivery and efficacy.
Main Results:
- Antioxidant functionalized nanoparticles demonstrate improved biocompatibility, stability, and targeted delivery.
- Biogenic nanoparticles combined with natural antioxidants show superior antioxidant potential.
- These novel nanoparticles effectively scavenge free radicals and mitigate ROS-induced damage.
Conclusions:
- Antioxidant functionalized nanoparticles represent a promising strategy to overcome antioxidant limitations.
- Biogenic nanoparticles offer a stable and effective platform for antioxidant delivery.
- Further research into these synergistic systems can lead to advanced therapeutic strategies for oxidative stress-related conditions.
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