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Updated: Dec 15, 2025

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
Published on: January 15, 2022
Assessing atherothrombotic burden with optical coherence tomography analysis may facilitate post-PCI prognostication
Briana Costello1,2, Zvonimir Krajcer1,2
1Department of Cardiology, Texas Heart Institute, Houston, Texas, USA.
Abstract:
Atherothrombotic burden (ATB) correlates with myocardial blush grade (MBG), a known predictor of mortality and outcome after ST-elevation myocardial infarction. Quantitative or semiquantitative analysis of ATB with optical coherence tomography may assist interventional cardiologists in post-PCI prognostication and, perhaps, in rendering more aggressive antiplatelet therapy. Future studies comparing treatment strategies for post-PCI patients with elevated ATB or depressed MBG may identify best practices after acute coronary syndromes.
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