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Ocular streptococcal infections.

S Jones1, E J Cohen, J J Arentsen

  • 1Cornea Service, Wills Eye Hospital, Philadelphia, Pennsylvania 19107.

Cornea
|January 1, 1988
PubMed
Summary

Streptococcal eye infections, including corneal ulcers and endophthalmitis, often lead to poor vision. Resistance to gentamicin, a common antibiotic, was observed in about one-third of cases.

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Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Microbiology

Background:

  • Streptococcal species are significant pathogens in ocular infections.
  • Commonly cause corneal ulcers, endophthalmitis, conjunctivitis, and dacryocystitis.

Purpose of the Study:

  • To retrospectively review ocular streptococcal infections.
  • To analyze the clinical outcomes and antibiotic sensitivities of these infections.

Main Methods:

  • Retrospective chart review of 53 patients with ocular streptococcal infections.
  • Analysis of diagnoses, visual outcomes, and antibiotic sensitivity testing results.

Main Results:

  • Corneal ulcers (43%) and endophthalmitis (34%) were the most frequent diagnoses.
  • Poor visual outcomes were common in streptococcal corneal ulcers and endophthalmitis.
  • 34% of streptococcal isolates showed resistance to gentamicin.

Conclusions:

  • Ocular streptococcal infections, particularly corneal ulcers and endophthalmitis, are associated with poor visual prognosis.
  • Antibiotic selection for these infections should consider potential gentamicin resistance.
  • Ophthalmologists should consider streptococcal etiology and antibiotic sensitivities in treatment and prophylaxis.

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