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Morphometric Analysis of the Corpus Callosum Using Cadaveric Brain: An Anatomical Study
Apurba Patra1, Rajan Kumar Singla2, Priti Chaudhary1
1Department of Anatomy, AIIMS, Bathinda, Punjab, India.
Asian Journal of Neurosurgery
|July 14, 2020
Summary
This study measured corpus callosum (CC) dimensions in human brains, establishing its precise location and revealing significant proportions and minor gender differences for anatomical reference.
Area of Science:
- Neuroanatomy
- Human Morphology
Background:
- The corpus callosum (CC) is a critical white matter structure connecting the cerebral hemispheres.
- Understanding its precise morphometry is essential for neurological studies.
Purpose of the Study:
- To measure longitudinal and vertical lengths of the brain hemisphere and CC.
- To determine the topographic location of the CC within brain hemispheres.
Main Methods:
- Dissection of 50 formalin-fixed human brains in the midsagittal plane.
- Measurement of key parameters including brain hemisphere dimensions and CC lengths/positions.
- Statistical analysis of morphometric data and correlations.
Main Results:
- Established mean values for brain hemisphere and CC measurements.
- Identified strong positive correlations between brain hemisphere dimensions and CC length (EZ/AB=0.45, EZ/CD=0.73).
- Observed statistically significant gender differences in two CC parameters (ZO and EZ).
Conclusions:
- Precise anatomical knowledge of CC morphometry provides essential baseline data.
- This data aids in the diagnosis and understanding of diseases affecting the CC.
