Related Experiment Video
Updated: Dec 15, 2025

Y-90 Radioembolization and PD-1 Inhibitor as Neoadjuvant Treatment in Hepatocellular Carcinoma
Published on: May 24, 2024
Roadmap to resuming care for liver diseases after coronavirus disease-2019
Devika Kapuria1, Steven Bollipo2,3, Atoosa Rabiee4
1Division of Gastroenterology and Hepatology, University of New Mexico, Albuquerque, New Mexico, USA.
Insights
Patients with chronic liver disease face risks from COVID-19 disruptions. This guide offers a roadmap for safely resuming liver care, focusing on outpatient services, transplantation, cancer care, and endoscopy.
Area of Science:
- Hepatology
- Infectious Diseases
- Public Health
Background:
- The COVID-19 pandemic significantly disrupted healthcare, particularly for vulnerable chronic liver disease patients.
- Chronic liver disease is an independent risk factor for COVID-19 related hospital mortality.
- Interim management changes, including telehealth and postponed procedures, were recommended for liver disease patients.
Purpose of the Study:
- To provide a roadmap for the safe resumption of clinical operations for patients with chronic liver disease.
- To minimize exposure risks for patients and healthcare professionals during the pandemic.
- To address specific care areas including outpatient services, liver transplantation, liver cancer, and endoscopy.
Main Methods:
- Review and synthesis of recommendations from national and international societies.
- Development of a phased approach for resuming clinical services.
- Emphasis on risk mitigation strategies for patient and provider safety.
Main Results:
- Concern exists regarding increased morbidity from delayed diagnosis and treatment.
- A potential delayed surge in decompensated liver disease hospitalizations is anticipated post-pandemic.
- The roadmap outlines strategies for safe outpatient care, transplantation, cancer management, and endoscopy.
Conclusions:
- Safe resumption of liver care requires a comprehensive, phased plan.
- Proactive planning is essential to mitigate risks associated with pandemic-related healthcare disruptions.
- Prioritizing patient and healthcare professional safety is paramount during service resumption.
Abstract:
The global pandemic of coronavirus disease-2019 (COVID-19) has led to significant disruptions in healthcare delivery. Patients with chronic liver diseases require a high level of care and are therefore particularly vulnerable to disruptions in medical services during COVID-19. Recent data have also identified chronic liver disease as an independent risk factor for COVID-19 related hospital mortality. In response to the pandemic, national and international societies have recommended interim changes to the management of patients with liver diseases. These modifications included the implementation of telehealth, postponement or cancelation of elective procedures, and other non-urgent patient care-related activities. There is concern that reduced access to diagnosis and treatment can also lead to increased morbidity in patients with liver diseases and we may witness a delayed surge of hospitalizations related to decompensated liver disease after the COVID-19 pandemic has receded. Therefore, it is paramount that liver practices craft a comprehensive plan for safe resumption of clinical operations while minimizing the risk of exposure to patients and health-care professionals. Here, we provide a broad roadmap for how to safely resume care for patients with chronic liver disease according to various phases of the pandemic with particular emphasis on outpatient care, liver transplantation, liver cancer care, and endoscopy.
More Related Videos
Related Concept Videos
Diseases of the Liver and Gallbladder
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Chronic Pancreatitis II: Collaborative Care
Assessment:
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
Myocarditis IV: Nursing Management
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test
Liver Regeneration
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are...

