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Updated: Dec 15, 2025

Simplified Human Neutrophil Extracellular Traps NETs Isolation and Handling
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Cellular Mechanisms of NETosis

Hawa Racine Thiam1, Siu Ling Wong2, Denisa D Wagner3,4,5

  • 1Cell and Developmental Biology Center, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health, Bethesda, Maryland 20892, USA; email: watermancm@nhlbi.nih.gov, hawa.racinethiam@nih.gov.

Annual Review of Cell and Developmental Biology
|July 15, 2020
PubMed
Summary

Neutrophil extracellular traps (NETs) are crucial for immunity but can also cause harm. Understanding NETosis mechanisms is key to developing therapies that control NET release for disease treatment.

Keywords:
PAD4cell biologycytoskeletoninnate immunityneutrophilneutrophil extracellular trapnucleus

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