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Related Experiment Video

Updated: Dec 15, 2025

Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography
03:35

Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography

Published on: December 1, 2023

513

Choroidal Differences between Spectral and Swept-source Domain Technologies.

Isabel Pinilla1,2, Ana Sanchez-Cano2,3, Gema Insa2

  • 1Department of Ophthalmology, Lozano Blesa University Hospital , Zaragoza, Spain.

Current Eye Research
|July 15, 2020
PubMed
Summary

Spectral domain OCT (SD-OCT) provides higher choroidal volume and thickness measurements than swept source OCT (SS-OCT) in healthy eyes. These differences are less pronounced in longer eyes and not linked to overall choroidal volume.

Keywords:
Spectral domain optical coherence tomographychoroidal thicknesschoroidal volumeenhanced depth imaginghealthy subjectsswept source optical coherence tomography

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Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Retinal Imaging

Background:

  • Accurate measurement of choroidal volume (CV) and choroidal thickness (CT) is crucial in ophthalmology.
  • Optical Coherence Tomography (OCT) is a key imaging modality for assessing choroidal parameters.
  • Comparing different OCT technologies, such as spectral domain OCT (SD-OCT) and swept source OCT (SS-OCT), is essential for understanding measurement variability.

Purpose of the Study:

  • To compare choroidal volume (CV) and choroidal thickness (CT) measurements between SD-OCT with enhanced depth imaging (EDI) and SS-OCT in healthy eyes.
  • To analyze these differences across all macular Early Treatment Diabetic Retinopathy Study (ETDRS) regions.
  • To investigate the influence of axial length (AL) and total CV on measurement discrepancies.

Main Methods:

  • 150 healthy eyes from participants aged 21-68 years were analyzed.
  • Ophthalmic examination included axial length (AL) measurement.
  • Macular imaging was performed using Spectralis SD-OCT (EDI) and DRI-Triton SS-OCT.
  • Choroidal volume (CV) and thickness (CT) were segmented manually (SD-OCT) and automatically (SS-OCT).

Main Results:

  • SD-OCT yielded statistically higher CV and CT values than SS-OCT across all ETDRS macular areas.
  • These differences persisted and were not solely related to total CV.
  • In eyes with longer axial lengths (AL), the discrepancies between the two OCT devices diminished, particularly in the subfoveal area.

Conclusions:

  • Choroidal measurements (CV, CT) obtained via SD-OCT are statistically higher than those from SS-OCT.
  • Both OCT techniques effectively visualize the choroidoscleral interface, showing high correlation despite measurement differences.
  • The observed differences are smaller in longer eyes and independent of total choroidal volume.