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Updated: Dec 14, 2025

Catalytic Scavenging of Plant Reactive Oxygen Species In Vivo by Anionic Cerium Oxide Nanoparticles
Published on: August 26, 2018
Cerium oxide nanoparticles and their importance in cell signaling pathways for predicting cellular behavior
Atefeh Pesaraklou1, Maryam M Matin1,2,3
1Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, 9177948974, Iran.
Abstract:
Cerium oxide nanoparticles (CeO2-NPs) have prolifically attracted immense interest of researchers due to their prominent anti-oxidant nature. However, these characteristics are accompanied by some ambiguities in other studies reporting their oxidant and toxic properties. In this regard previous literature has pointed to the importance of the NPs morphology and environmental conditions as well as biomolecules that induce a different response by initiating a cascade of activities. Therefore, due to the fact that signaling proteins are key mediators in cellular responses, the cognizance of the CeO2-NP-targeted signaling pathways could facilitate predicting the cellular behavior and thus more efficient applications of these NPs for clinical purposes. Consequently, a comprehensive review is necessary in this field, to clarify the impacts of CeO2-NPs on various signaling pathways.
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