Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Heart Failure I: Introduction01:27

Heart Failure I: Introduction

595
Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
595
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

2.5K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
2.5K
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

558
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
558
Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

344
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
344
Heart Failure IV: Classification and Diagnostic Evaluation01:30

Heart Failure IV: Classification and Diagnostic Evaluation

189
Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
189
Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

2.1K
The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
2.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Diagnosis and treatment of cardiac amyloidosis: position statement of the German Cardiac Society (DGK).

Clinical research in cardiology : official journal of the German Cardiac Society·2021
Same author

[Erratum to: Cognitive dysfunction in heart failure-Causes and sequelae].

Der Internist·2020
Same author

[Evidence-based drug therapy for heart failure-an update].

Herz·2019
Same author

[Update on heart failure].

Herz·2018
Same author

[Pulmonary hypertension associated with left heart disease: recommendations of the Cologne Consensus Conference 2016].

Deutsche medizinische Wochenschrift (1946)·2016
Same author

[83-year-old patient with head laceration after syncope].

Deutsche medizinische Wochenschrift (1946)·2014
Same journal

Der Internist·2024
Same journal

Der Internist·2024
Same journal

Der Internist·2024
Same journal

Der Internist·2024
Same journal

Der Internist·2024
Same journal

Der Internist·2024
See all related articles

Related Experiment Video

Updated: Dec 14, 2025

Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure
09:37

Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure

Published on: December 2, 2014

28.4K

[Cognitive dysfunction in heart failure-Causes and sequelae].

S M Wedegärtner1, M Böhm1, I Kindermann2

  • 1Klinik für Innere Medizin III (Kardiologie, Angiologie, internistische Intensivmedizin), Universitätsklinikum des Saarlandes, Universität des Saarlandes, Homburg (Saar), Deutschland.

Der Internist
|July 16, 2020
PubMed
Summary
This summary is machine-generated.

Approximately 40% of heart failure patients experience cognitive deficits, impacting adherence and increasing mortality. Early detection via neuropsychological screening can lead to targeted treatments and improved patient care.

Keywords:
Attention deficitsComorbidityMedication adherenceMemory impairmentNeuropsychological testing

More Related Videos

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
07:30

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Published on: April 23, 2021

3.3K
Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs
14:35

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs

Published on: April 17, 2021

8.9K

Related Experiment Videos

Last Updated: Dec 14, 2025

Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure
09:37

Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure

Published on: December 2, 2014

28.4K
Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
07:30

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Published on: April 23, 2021

3.3K
Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs
14:35

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs

Published on: April 17, 2021

8.9K

Area of Science:

  • Cardiology
  • Neuropsychology

Background:

  • Cognitive deficits, including memory and attention impairment, affect nearly 40% of heart failure patients.
  • These deficits are linked to higher rehospitalization rates and increased mortality.
  • Potential causes include poor disease-specific knowledge and inadequate strategies for managing symptoms.

Purpose of the Study:

  • To highlight the prevalence and impact of cognitive impairment in heart failure.
  • To discuss the multifactorial pathogenesis of these deficits.
  • To emphasize the importance of early detection and management.

Main Methods:

  • Review of existing literature on heart failure and cognitive function.
  • Discussion of the role of heart failure, cardiovascular risk factors, and comorbidities.
  • Emphasis on the utility of neuropsychological screening tests.

Main Results:

  • Cognitive deficits are common in heart failure patients.
  • These deficits can negatively influence adherence to treatment and patient outcomes.
  • Heart failure, cardiovascular risks, and comorbidities contribute to cognitive impairment.

Conclusions:

  • Neuropsychological screening can identify cognitive impairment in heart failure.
  • Early identification allows for targeted treatment strategies.
  • Optimized care involves patients, caregivers, and healthcare providers.