Phyto-fabricated Cr₂O₃ nanoparticle for multifunctional biomedical applications

Area of Science:

• Nanotechnology
• Materials Science
• Biomedical Engineering

Background:

• The development of novel nanomaterials for nanomedicine is crucial.
• Biogenic synthesis offers a sustainable approach to nanoparticle production.

Purpose of the Study:

• To biosynthesize chromium oxide nanoparticles (Cr2O3 NPs) using Hyphaene thebaica.
• To evaluate the nanomedicinal potential of these biogenic Cr2O3 NPs.

Main Methods:

• Characterization using X-ray diffraction, spectroscopy (FTIR, EDS, UV-Vis), and electron microscopy (SEM, TEM).
• Assessment of biological properties through in vitro assays, including antimicrobial, antioxidant, and biocompatibility tests.
• Zeta potential measurements for surface charge analysis.

Main Results:

• Successfully synthesized Cr2O3 NPs with sizes ranging from 25-38 nm.
• Demonstrated broad-spectrum antimicrobial activity and significant antioxidant properties.
• Observed slight inhibition of poliovirus and good biocompatibility at low concentrations.

Conclusions:

• Biogenic Cr2O3 NPs exhibit multifunctional properties.
• These nanoparticles show promise for various nanomedicinal applications.