Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Hypertension: Classification and Pathogenesis01:30

Pulmonary Hypertension: Classification and Pathogenesis

472
Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...
472
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

4.0K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
4.0K
COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

1.7K
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
1.7K
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

3.4K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
3.4K
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

249
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
249
Factors Affecting Pulmonary Ventilation01:19

Factors Affecting Pulmonary Ventilation

2.6K
Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
2.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Is Increased BMI a Risk Factor for Developing Severe Clostridioides Difficile Infection? A Retrospective Study.

Journal of community hospital internal medicine perspectives·2023
Same author

An Uncommon Presentation of Pulmonary Tularemia: A Case Report and Literature Review.

Cureus·2022
Same author

Splenic Laceration: A Rare Complication of Colonoscopy.

Cureus·2022
Same author

Eculizumab for refractory thrombosis in antiphospholipid syndrome.

Blood advances·2022
Same author

Hypogammaglobulinemia following COVID-19 infection in a patient on maintenance rituximab.

SAGE open medical case reports·2021
Same author

Efficacy of subcutaneous interferon-beta in COVID-19: a meta-analysis and systematic review.

Journal of community hospital internal medicine perspectives·2021

Related Experiment Video

Updated: Dec 14, 2025

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

20.7K

Multifactorial Pulmonary Hypertension in Systemic Sclerosis.

Habiba Hussain1, Ronald Espinosa2, Subramanyam Chittivelu2

  • 1Internal Medicine, University of Illinois College of Medicine, Peoria, USA.

Cureus
|July 17, 2020
PubMed
Summary

Multifactorial pulmonary hypertension, driven by multiple causes, can rapidly progress. Early diagnosis is crucial for managing this complex pulmonary arterial hypertension (PAH) case.

Keywords:
interstitial lung diseasemultifactorial pulmonary hypertensionpulmonary arterial hypertensionsclerodermasystemic sclerosis

More Related Videos

Right Ventricular Systolic Pressure Measurements in Combination with Harvest of Lung and Immune Tissue Samples in Mice
10:20

Right Ventricular Systolic Pressure Measurements in Combination with Harvest of Lung and Immune Tissue Samples in Mice

Published on: January 16, 2013

25.8K
Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat
08:34

Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat

Published on: November 18, 2018

7.5K

Related Experiment Videos

Last Updated: Dec 14, 2025

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

20.7K
Right Ventricular Systolic Pressure Measurements in Combination with Harvest of Lung and Immune Tissue Samples in Mice
10:20

Right Ventricular Systolic Pressure Measurements in Combination with Harvest of Lung and Immune Tissue Samples in Mice

Published on: January 16, 2013

25.8K
Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat
08:34

Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat

Published on: November 18, 2018

7.5K

Area of Science:

  • Cardiology
  • Pulmonology
  • Medical Diagnostics

Background:

  • Pulmonary hypertension (PH) is a progressive condition with complex, multifactorial causes.
  • The interplay of multiple etiologies in PH progression is not well-documented.
  • Diagnosing PH becomes challenging with co-existing, plausible causal factors.

Observation:

  • A case of pulmonary arterial hypertension (PAH) presented with rapidly worsening symptoms.
  • The patient's condition highlighted diagnostic complexities in multifactorial PH.
  • Simultaneous comorbidities complicated the attribution of PH etiology.

Findings:

  • Rapid symptom progression in PH can be linked to multifactorial etiology.
  • A thorough diagnostic workup is essential when multiple PH causes are suspected.
  • Early identification of contributing factors is key for effective management.

Implications:

  • This case underscores the need for comprehensive diagnostic strategies in PH.
  • Understanding multifactorial PH is critical for improving patient outcomes.
  • Further research is needed on the impact of combined etiologies in PH progression.