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Headache in Behçet's Disease.

Marianna Vinokur1, John Glenn Burkett2

  • 1Department of Neurology, Allegheny Health Network, Pittsburgh, PA, USA. Marianna.Vinokur2@AHN.ORG.

Current Pain and Headache Reports
|July 17, 2020
PubMed
Summary
This summary is machine-generated.

Headache is a common neurological symptom in Behcet's disease (BD). While often a primary headache disorder, worsening headaches may indicate increased Behcet's disease activity, necessitating further investigation into neuro-Behcet's disease.

Keywords:
Behcet’s syndromeCerebral venous sinus thrombosisChronic daily headacheEpisodic headacheHeadacheMigraineNeuro-Behcet’sUveitis

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Area of Science:

  • Neurology
  • Rheumatology
  • Systemic Inflammatory Disorders

Background:

  • Behcet's disease (BD) is a chronic, systemic inflammatory disorder of unknown cause.
  • Prevalence is highest along the ancient Silk Road, particularly in the Middle East.
  • Neurologic manifestations, known as neuro-Behcet's disease (NBD), occur occasionally.

Purpose of the Study:

  • To describe the diverse neurologic manifestations of Behcet's syndrome.
  • To specifically focus on headache syndromes associated with Behcet's disease.

Main Methods:

  • Review of recent studies focusing on neuro-Behcet's disease (NBD) characterization.
  • Analysis of headache presentations in patients with Behcet's disease (BD).

Main Results:

  • Headache is the most frequent neurological symptom reported in BD.
  • Most headaches in BD patients are primary headache disorders, including tension-type and migraines.
  • Worsening headaches can signify increased BD activity; cerebral venous thrombosis is the most common secondary cause of headache in BD.

Conclusions:

  • Headache is a key neurological symptom in Behcet's disease.
  • Distinguishing primary headaches from those indicative of NBD activity is crucial.
  • Further research into NBD is needed to better characterize this rare disorder.