Related Experiment Video

Updated: Dec 14, 2025

Inactivation of Pathogens via Visible-Light Photolysis of Riboflavin-5′-Phosphate
08:25

Inactivation of Pathogens via Visible-Light Photolysis of Riboflavin-5′-Phosphate

Published on: April 6, 2022

2.1K

Rapid inactivation of SARS-CoV-2 with deep-UV LED irradiation

Hiroko Inagaki1, Akatsuki Saito2,3, Hironobu Sugiyama1,4

  • 1M&N Collaboration Research Laboratory, Department of Medical Environment Innovation, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.

Emerging Microbes & Infections
|July 17, 2020
PubMed

Insights

Deep ultraviolet light-emitting diodes (DUV-LEDs) at 280nm rapidly inactivate SARS-CoV-2, the virus causing COVID-19. This technology offers a promising method for preventing airborne and surface transmission of the virus.

Area of Science:

  • Microbiology
  • Public Health
  • Biomedical Engineering

Background:

  • The global spread of COVID-19 necessitates effective strategies for preventing SARS-CoV-2 transmission.
  • Current methods for viral inactivation face challenges in rapid and widespread application.
  • Aerosol and contact transmission routes are significant concerns for infectious disease control.

Discussion:

  • This study investigated the efficacy of deep ultraviolet light-emitting diodes (DUV-LEDs) for SARS-CoV-2 inactivation.
  • The research focused on a specific wavelength (280 nm) and its effectiveness against the virus.
  • In vitro testing was performed using SARS-CoV-2 samples from a COVID-19 patient.

Key Insights:

  • Irradiation with 280 nm DUV-LED light demonstrated rapid inactivation of SARS-CoV-2.
  • The findings confirm the virucidal potential of specific DUV-LED wavelengths.
  • This provides a scientific basis for developing new disinfection technologies.

Outlook:

  • Development of DUV-LED based devices is expected to enhance prevention of airborne virus transmission.
  • Such devices could also mitigate infection risks from contaminated surfaces.
  • Further research may explore DUV-LED applications in various settings for infectious disease control.
Keywords:
COVID-19SARS-CoV-2antiviral efficacycontact transmissiondeep-UV LEDfomite infectioninactivation

More Related Videos

LED-Based In Vitro Screening for Assessing Photoactivable Molecules in Bacterial Photodynamic Inactivation05:13

LED-Based In Vitro Screening for Assessing Photoactivable Molecules in Bacterial Photodynamic Inactivation

Published on: January 24, 2025

630
Author Spotlight: Advancing Pathogen Diagnostics with Standardized LAMP05:34

Author Spotlight: Advancing Pathogen Diagnostics with Standardized LAMP

Published on: September 8, 2023

1.1K

Related Concept Videos

Physical Methods for Controlling Microbial Growth: Radiation and Filtration01:26

Physical Methods for Controlling Microbial Growth: Radiation and Filtration

Radiation and filtration are essential tools for microbial control, targeting microorganisms through distinct mechanisms. Radiation eliminates microbes by damaging their DNA, either killing them or inhibiting their growth. Based on wavelength, radiation is classified into two types: nonionizing and ionizing radiation.Non-ionizing radiation, such as UV radiation (200–400 nm), is absorbed by DNA, causing defects that effectively disinfect surfaces, air, and water, including safety cabinets.
879