Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Potentiometry: Membrane Electrodes01:15

Potentiometry: Membrane Electrodes

1.4K
Membrane electrodes, also known as p-ion electrodes, use membranes that selectively interact with free analyte ions, generating a potential difference across the membrane. The resulting membrane potential, known as the asymmetry potential, is not zero even when analyte concentrations on both sides of the membrane are equal. The membrane's response is typically not selective to a single analyte but proportional to the concentration of all ions in the sample solution capable of interacting at...
1.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

AI-generated clinical summaries: errors and susceptibility to speech and speaker variability.

BMJ health & care informatics·2026
Same author

Efficacy of Interleukin 8 (IL-8) in the detection of urinary tract infection.

Frontiers in immunology·2026
Same author

Identification and velocity measurement of microplastics based on machine learning.

Water research·2025
Same author

A high-resolution network with adaptive spatial channel fusion for retinal vessel segmentation.

Biomedical physics & engineering express·2025
Same author

Learning and inference with correlated neural variability.

PNAS nexus·2025
Same author

Evaluation the inhibitory effect of nicardipine on the metabolism of quetiapine.

Frontiers in pharmacology·2025
Same journal

Energy-equivalent cyclic pulsed electric fields enable reversible membrane permeabilization and sustainable protein release from microalgae.

Bioelectrochemistry (Amsterdam, Netherlands)·2026
Same journal

Electrochemical monitoring of electroactive compounds secreted by Escherichia coli during the aerobic-to-anaerobic transition.

Bioelectrochemistry (Amsterdam, Netherlands)·2026
Same journal

Bioelectrochemical Sensing Dynamics of SARS-CoV-2 Biomarkers.

Bioelectrochemistry (Amsterdam, Netherlands)·2026
Same journal

Meta-analysis and interpretable machine learning model of organic removal and power generation in photosynthetic microbial fuel cells.

Bioelectrochemistry (Amsterdam, Netherlands)·2026
Same journal

Surfactant-doped PEDOT films as dual-function bioelectronic coatings with enhanced charge storage capacity and antibiofilm activity.

Bioelectrochemistry (Amsterdam, Netherlands)·2026
Same journal

Design and application of a FA-based molecularly imprinted sensor for screening anti-Fusariumoxysporum substances from Lanzhou lily endophytes.

Bioelectrochemistry (Amsterdam, Netherlands)·2026
See all related articles

Related Experiment Video

Updated: Dec 14, 2025

Membrane Transport Processes Analyzed by a Highly Parallel Nanopore Chip System at Single Protein Resolution
11:55

Membrane Transport Processes Analyzed by a Highly Parallel Nanopore Chip System at Single Protein Resolution

Published on: August 16, 2016

12.0K

Nanoparticle-based 3D membrane for impedimetric biosensor applications.

Lu Cao1, Janice Kiely1, Martina Piano1

  • 1Institute of Bio-Sensing Technology, University of the West of England, Frenchay Campus, Bristol BS16 1QY, United Kingdom.

Bioelectrochemistry (Amsterdam, Netherlands)
|July 17, 2020
PubMed
Summary
This summary is machine-generated.

This study developed novel nano-ZnO/CuO and nano-ZnO biosensors using sonication. The nano-ZnO/CuO biosensor achieved a lower limit of detection for C-reactive protein (CRP) detection.

Keywords:
CRP detectionImpedance spectroscopyPhase changeZnO/CuO nitrocellulose membrane

More Related Videos

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor
08:22

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor

Published on: February 16, 2018

12.5K
Native Cell Membrane Nanoparticles System for Membrane Protein-Protein Interaction Analysis
07:31

Native Cell Membrane Nanoparticles System for Membrane Protein-Protein Interaction Analysis

Published on: July 16, 2020

6.4K

Related Experiment Videos

Last Updated: Dec 14, 2025

Membrane Transport Processes Analyzed by a Highly Parallel Nanopore Chip System at Single Protein Resolution
11:55

Membrane Transport Processes Analyzed by a Highly Parallel Nanopore Chip System at Single Protein Resolution

Published on: August 16, 2016

12.0K
Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor
08:22

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor

Published on: February 16, 2018

12.5K
Native Cell Membrane Nanoparticles System for Membrane Protein-Protein Interaction Analysis
07:31

Native Cell Membrane Nanoparticles System for Membrane Protein-Protein Interaction Analysis

Published on: July 16, 2020

6.4K

Area of Science:

  • Materials Science
  • Nanotechnology
  • Biosensor Technology

Background:

  • Nitrocellulose membranes are widely used in biosensor fabrication.
  • Nanoparticle-based biosensors offer enhanced sensitivity and detection capabilities.
  • Developing cost-effective and efficient biosensor fabrication methods is crucial for widespread application.

Purpose of the Study:

  • To compare the performance of nano-ZnO/CuO and nano-ZnO nitrocellulose membrane biosensors.
  • To evaluate the efficacy of a simple sonication technique for biosensor fabrication.
  • To determine the limit of detection for C-reactive protein (CRP) using the developed biosensors.

Main Methods:

  • Fabrication of nano-ZnO/CuO and nano-ZnO nitrocellulose membranes via sonication.
  • Characterization of membranes using scanning electron microscopy (SEM) and energy-dispersive spectroscopy (EDS).
  • Impedance spectroscopy was employed to analyze biosensor performance and C-reactive protein (CRP) detection.

Main Results:

  • Sonication technique successfully produced nano-ZnO/CuO and nano-ZnO membranes with gradated nanoparticle distribution.
  • Impedance spectroscopy showed a greater than two-fold enhancement in output signal due to sonication.
  • The nano-ZnO/CuO biosensor demonstrated a lower limit of detection (16 pg/mL) for CRP compared to the nano-ZnO biosensor (27 pg/mL).

Conclusions:

  • The sonication technique is a viable and cost-effective method for fabricating enhanced nano-ZnO/CuO and nano-ZnO biosensors.
  • The nano-ZnO/CuO composite material significantly improves biosensor performance for C-reactive protein (CRP) detection.
  • These findings highlight the potential of nanoparticle-enhanced nitrocellulose membrane biosensors for sensitive biomarker detection.