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Double coronary thrombosis in a patient with Behçet's disease

Luís Abreu1, Bruno Marmelo1, Júlio Gil1

  • 1Serviço Cardiologia, Centro Hospitalar Tondela Viseu, Viseu, Portugal.

Revista Portuguesa De Cardiologia
|July 18, 2020
PubMed

Insights

This case study highlights a rare cardiac complication of Behçet's disease (BD). A patient with BD experienced ST-elevation myocardial infarction (STEMI) and underwent successful percutaneous coronary intervention.

Area of Science:

  • Cardiology
  • Rheumatology
  • Immunology

Background:

  • Behçet's disease is a rare multisystem autoinflammatory disorder.
  • Cardiac involvement in Behçet's disease, though uncommon, presents significant life-threatening risks.
  • Current treatments focus on empirical immunosuppression to manage vasculitis.

Observation:

  • A 42-year-old male with a history of Behçet's disease presented with ST-elevation myocardial infarction (STEMI).
  • The patient exhibited combined thrombosis in the left anterior descending and right coronary arteries.
  • He required two percutaneous coronary interventions with drug-eluting stent implantation due to a high thrombotic burden.

Findings:

  • The patient's clinical course during hospitalization was favorable, with no evidence of systolic dysfunction upon discharge.
  • Follow-up assessments indicated no new cardiovascular events, suggesting successful management of the acute event.

Implications:

  • This case underscores the importance of considering cardiac complications in Behçet's disease patients presenting with ischemic symptoms.
  • Aggressive interventional management, including percutaneous coronary intervention, can be effective in treating acute coronary syndromes in this population.
  • Further research into the specific mechanisms of cardiac involvement in Behçet's disease is warranted to optimize treatment strategies.

Keywords:
Acute coronary syndromeBehçet diseaseDoença de BehçetIntervenção coronária percutânea primáriaPrimary percutaneous coronary interventionSíndrome coronária aguda

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