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Updated: Dec 14, 2025

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Spontaneous sphenoid meningoencephalocele with sepsis
Monica Shah1, Marco A Tadeo Bermúdez Borjas2, Karen Brust1
1Department of Infectious Diseases, Baylor Scott and White Medical Center-TempleTempleTexas.
Abstract:
Streptococci bacteremia is an unusual source of sepsis from spontaneous cerebrospinal fluid (CSF) rhinorrhea due to sphenoid meningoencephalocele. A spontaneous cause of CSF rhinorrhea should be on the differential along with trauma and congenital and neoplastic lesions. Moxifloxacin 400 mg daily for 2 weeks has a satisfactory CSF penetration to treat Streptococcus viridans bacteremia due to CSF rhinorrhea.
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