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Updated: Dec 14, 2025

An All-in-one Sample Holder for Macromolecular X-ray Crystallography with Minimal Background Scattering
Published on: July 6, 2019
Advances in methods for atomic resolution macromolecular structure determination
Michael C Thompson1, Todd O Yeates2,3, Jose A Rodriguez2,3
1Department of Chemistry and Chemical Biology, University of California, Merced, CA, USA.
Abstract:
Recent technical advances have dramatically increased the power and scope of structural biology. New developments in high-resolution cryo-electron microscopy, serial X-ray crystallography, and electron diffraction have been especially transformative. Here we highlight some of the latest advances and current challenges at the frontiers of atomic resolution methods for elucidating the structures and dynamical properties of macromolecules and their complexes.
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