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Coupling Pressure Sensing with Optical Coherence Tomography to Evaluate the Internal Nasal Valve
Amir A Hakimi1, Giriraj K Sharma1,2, Tuan Ngo1
1Beckman Laser Institute & Medical Clinic, University of California - Irvine, CA, USA.
The Annals of Otology, Rhinology, and Laryngology
|July 19, 2020
Summary
This study shows that a combined endoscopic optical coherence tomography and pressure sensor system accurately measures internal nasal valve area and pressure during breathing. This tool quantifies the dynamic nasal valve behavior and airflow.
Area of Science:
- Rhinology
- Medical Imaging
- Biomedical Engineering
Background:
- Nasal airway obstruction is a common condition affecting quality of life.
- Accurate measurement of the internal nasal valve (INV) is crucial for diagnosis and treatment.
- Current methods for assessing INV dynamics are limited.
Purpose of the Study:
- To evaluate an endoscopic long-range optical coherence tomography (OCT) system combined with a pressure sensor.
- To concurrently measure internal nasal valve cross-sectional area and intraluminal pressure.
- To assess the dynamic behavior of the INV during respiration.
Main Methods:
- Developed and calibrated an Arduino-based pressure sensor.
- Performed concurrent OCT imaging and pressure transduction in eight healthy adults.
- Segmented the INV using Mimics software to measure cross-sectional area.
- Correlated INV cross-sectional area measurements with pressure recordings.
Main Results:
- Mean INV cross-sectional area during forced inspiration was 6.49 mm².
- Mean pressure change between normal and forceful inspiration was 12.27 mmHg.
- Demonstrated reproducible direct correlation between pressure and cross-sectional area.
Conclusions:
- A direct correlation exists between INV cross-sectional area and nasal airflow during inspiration.
- Endoscopic OCT with a pressure sensor is a valuable tool for quantifying INV dynamic behavior.
- This system aids in understanding nasal airflow dynamics and potential obstructions.
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