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Reflux as a Risk Factor for Morbidity after Pediatric Tonsillectomy: A National Cohort of Inpatients
Stephen R Chorney1,2, Karen B Zur1,2, Adva Buzi1,2
1Division of Otolaryngology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, U.S.A.
Insights
Gastroesophageal reflux (GER) increases inpatient complications and hospital stays for children undergoing tonsillectomy. Children with GER experience poorer outcomes, necessitating careful preoperative planning.
Area of Science:
- Otolaryngology
- Pediatric Surgery
- Gastroenterology
Background:
- Gastroesophageal reflux (GER) is a known risk factor for adverse outcomes after pediatric tonsillectomy.
- Understanding these risks is crucial for optimizing surgical care and patient management.
Purpose of the Study:
- To investigate the impact of GER on outcomes following pediatric tonsillectomy.
- To analyze hospitalization duration and associated costs in children with GER undergoing tonsillectomy.
Main Methods:
- A retrospective cross-sectional study utilizing the Healthcare Cost and Utilization Project (HCUP) Kids' Inpatient Databases (KID).
- Data from 2012 and 2016 were analyzed for children undergoing tonsillectomy, comparing those with and without a GER diagnosis.
Main Results:
- Children with GER (7.9%) had higher rates of respiratory complications, aspiration pneumonitis, and hypoxemia post-tonsillectomy.
- Patients with GER experienced longer hospital admissions (3.8 vs. 2.3 days) and significantly higher total hospital charges ($47,129 vs. $27,584).
- Reflux was a significant predictor of aspiration pneumonitis, hypoxemia, need for ventilation, and extended admission duration.
Conclusions:
- Children with GER face significantly increased inpatient complications and longer hospital stays after tonsillectomy.
- These findings underscore the importance of preoperative assessment and tailored management strategies for pediatric tonsillectomy patients with GER.
Objective:
Gastroesophageal reflux (GER) has been identified as a risk factor for complications following pediatric tonsillectomy. The primary objective of this study was to examine outcomes after tonsillectomy among children with GER using a nationwide database. Secondary objectives included analyzing duration of hospitalization and total charges after admission.
Methods:
A cross-sectional review of the Healthcare Cost and Utilization Project (HCUP) Kids' Inpatient Databases (KID) from 2012 and 2016.
Results:
A total of 21,232 children had a tonsillectomy with or without adenoidectomy, with 1683 (7.9%) diagnosed with GER. Average age for patients with reflux was 4.4 years and for those without was 5.6 years (P < .001). The rate of primary hemorrhage was not statistically different between groups (P = .87). Patients with reflux were more likely to have respiratory complications (P = .03), aspiration pneumonitis (P < .001), and hypoxemia (P < .001) during their hospital course. Noninvasive ventilation and reintubation also occurred more frequently in this population (P < .001). Children with reflux had a longer duration of postoperative admission (3.8 vs. 2.3 days, P < .001) and higher total hospital charges ($47,129 vs. $27,584, P < .001). Multivariable regression analysis determined that reflux remained a statistically significant indicator of aspiration pneumonitis, hypoxemia, invasive and non-invasive ventilation, as well as length of admission.
Conclusion:
Children with GER were significantly more likely to experience inpatient complications following tonsillectomy. Further, length of admission was higher compared to children without reflux. These results suggest that children with GER experience poorer outcomes after tonsillectomy and highlight the role for appropriate preoperative counseling and planning in this patient population. Laryngoscope, 131:907-910, 2021.
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