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Related Concept Videos

Regulation of the Cardiovascular System01:27

Regulation of the Cardiovascular System

3.3K
The regulation of the cardiovascular system allows the body to adapt to various demands and maintain homeostasis.
The regulation of the cardiovascular system involves the autonomic nervous system (ANS), baroreceptors, and chemoreceptors, ensuring that heart rate and blood pressure are appropriately modulated in response to varying physiological demands.
The ANS comprises two main divisions: the sympathetic and parasympathetic nervous systems. The sympathetic nervous system enhances...
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Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

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The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
278
Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

261
Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
261
Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

226
Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
226
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

756
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
756
Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

255
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
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Related Experiment Video

Updated: Dec 14, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
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Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2

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SARS-CoV-2 and the cardiovascular system.

Anouar Hafiane1

  • 1McGill University, Canada.

Clinica Chimica Acta; International Journal of Clinical Chemistry
|July 19, 2020
PubMed
Summary

COVID-19, caused by SARS-CoV-2, can trigger severe immune responses and multi-organ dysfunction. This review examines the link between COVID-19 and increased cardiovascular disease risks and mortality.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Immunology

Background:

  • COVID-19 is a global health emergency caused by SARS-CoV-2.
  • The virus primarily infects the respiratory tract via the ACE2 receptor.
  • An overactive immune response, or cytokine storm, contributes to COVID-19 severity and multi-organ dysfunction.

Purpose of the Study:

  • To review the existing evidence on the association between COVID-19 and cardiovascular complications.
  • To explore the potential mechanisms linking SARS-CoV-2 infection to cardiac morbidity and mortality.

Main Methods:

  • Literature review of studies investigating COVID-19 and cardiovascular outcomes.
  • Analysis of data on the impact of SARS-CoV-2 on the cardiovascular system.
Keywords:
ACE2COVID-19Myocardial injurySARS-CoV-2Severe acute respiratory syndromeTroponin

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Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
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Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses

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Monitoring Changes in Human Umbilical Vein Endothelial Cells upon Viral Infection Using Impedance-Based Real-Time Cell Analysis
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Related Experiment Videos

Last Updated: Dec 14, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
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Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2

Published on: November 5, 2021

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Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
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Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses

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Monitoring Changes in Human Umbilical Vein Endothelial Cells upon Viral Infection Using Impedance-Based Real-Time Cell Analysis
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Monitoring Changes in Human Umbilical Vein Endothelial Cells upon Viral Infection Using Impedance-Based Real-Time Cell Analysis

Published on: May 5, 2023

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Main Results:

  • Growing evidence indicates a significant increase in cardiovascular disease morbidity and mortality among COVID-19 patients.
  • SARS-CoV-2 infection can lead to direct cardiac damage and exacerbate pre-existing cardiovascular conditions.

Conclusions:

  • COVID-19 poses a substantial threat to cardiovascular health.
  • Further research is needed to fully understand and manage the cardiovascular sequelae of SARS-CoV-2 infection.