Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

6.7K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
6.7K
The Thyroid Gland01:23

The Thyroid Gland

6.3K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
6.3K
Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

4.6K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
4.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Exploring restrictive practices in inpatient eating disorder services: a scoping review.

Eating disorders·2026
Same author

Perceptions and Barriers to Intraoperative Non-technical Skills Feedback in General Surgery: A Mixed-Methods Study.

The Journal of surgical research·2026
Same author

Application and Evaluation of a Formative Feedback Rubric on Nontechnical Skills Using Retrospective SIMPL App Data in General Surgery Residents.

Journal of surgical education·2026
Same author

Identifying Barriers and Facilitators to Providing Psychologically Safe Care in Inpatient Mental Healthcare. A Theoretical Domains Framework-Informed Qualitative Study.

Journal of clinical nursing·2026
Same author

An Investigation of Elevated Serum Copper Levels Following Bariatric Surgery.

Obesity surgery·2026
Same author

An Exploration of Danish Forensic Hospital Staffs' Clinical Decision-Making about the Least Restrictive Alternative Principle.

Issues in mental health nursing·2026

Related Experiment Video

Updated: Dec 14, 2025

Mixed Reality Assisted Radical Endoscopic Thyroidectomy
08:06

Mixed Reality Assisted Radical Endoscopic Thyroidectomy

Published on: January 31, 2025

570

Postoperative thyroid hormone supplementation rates following thyroid lobectomy.

Madeleine Wilson1, Anery Patel2, Whitney Goldner2

  • 1University of Nebraska Medical Center, USA.

American Journal of Surgery
|July 21, 2020
PubMed
Summary

Thyroid hormone supplementation is often needed after thyroid lobectomy, especially for cancer patients. Higher preoperative TSH, thyroiditis, smaller remnant lobe, and malignancy predict the need for hormone replacement.

Keywords:
Postsurgical hypothyroidismThyroid carcinomaThyroid lobectomyThyroid noduleThyroidectomy

More Related Videos

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
05:12

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy

Published on: May 12, 2023

4.4K
Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
04:09

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter

Published on: September 20, 2024

656

Related Experiment Videos

Last Updated: Dec 14, 2025

Mixed Reality Assisted Radical Endoscopic Thyroidectomy
08:06

Mixed Reality Assisted Radical Endoscopic Thyroidectomy

Published on: January 31, 2025

570
Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
05:12

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy

Published on: May 12, 2023

4.4K
Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
04:09

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter

Published on: September 20, 2024

656

Area of Science:

  • Endocrinology
  • Surgical Oncology
  • Thyroid Surgery

Background:

  • Thyroid lobectomy is a common procedure for benign nodules, indeterminate nodules, or low-risk thyroid cancer.
  • Factors influencing the need for thyroid hormone supplementation post-lobectomy require further elucidation.

Purpose of the Study:

  • To identify predictors of thyroid hormone supplementation requirement after thyroid lobectomy.
  • To analyze the association between preoperative factors, final pathology, and postoperative thyroid hormone needs.

Main Methods:

  • Retrospective cohort study of 100 patients undergoing thyroid lobectomy (2016-2017).
  • Postoperative thyroid hormone supplementation assessed based on thyroid stimulating hormone (TSH) goals for benign and malignant pathology.
  • Univariate and multivariate logistic regression analyses were performed.

Main Results:

  • 47% of patients required thyroid hormone supplementation post-lobectomy.
  • Higher rates of supplementation were observed in patients with cancer (73%) versus benign pathology (38%).
  • Predictors included higher preoperative TSH, presence of thyroiditis, smaller remnant thyroid lobe volume, and malignancy.

Conclusions:

  • Post-thyroid lobectomy hormone supplementation is linked to preoperative TSH, thyroiditis, remnant volume, and malignancy.
  • Most patients with thyroid carcinoma require supplementation to meet TSH goals.
  • The majority of patients with benign pathology do not require supplementation.