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Updated: Dec 14, 2025
Author Spotlight: Experimental Approaches for the Synthesis of Low-Valent Metal-Organic Frameworks from Multitopic Phosphine Linkers
Published on: May 12, 2023
Study and modular synthesis of unsymmetrical bis(phosphino)pyrrole ligands
Hilary D Fokwa1, Julia F Vidlak, Sophie C Weinberg
1Department of Chemistry, University of Richmond, Richmond, Virginia 23173, USA. miles.johnson@richmond.edu.
Abstract:
We report the facile and modular synthesis of unsymmetrical 1,2-bis(phosphino)pyrrole ligands and their coordination chemistry. These ligands offer a promising alternative to their 1,2-bis(phosphino)benzene congeners, retaining a similar steric profile with attenuated electron donation. Proof-of-principle application of a bis(phosphino)pyrrole ligand in a nickel-catalyzed C-N cross-coupling reaction under mild conditions is demonstrated.
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