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Super-resolution Fluorescence Microscopy

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Updated: Dec 14, 2025

Measurement of Scattering Nonlinearities from a Single Plasmonic Nanoparticle

Measurement of Scattering Nonlinearities from a Single Plasmonic Nanoparticle

Published on: January 3, 2016

Plasmonics meets super-resolution microscopy in biology.

Miaoyan Wang¹, Meiqi Li¹, Shan Jiang¹

¹Department of Biomedical Engineering, College of Engineering, Peking University, 100871 Beijing, China.

Micron (Oxford, England : 1993)

|July 21, 2020

Summary

Plasmonics enhances super-resolution microscopy by manipulating light with metallic nanostructures. This review covers plasmonic nanoprobes and their role in overcoming optical limits for biological imaging.

Keywords:

Plasmon-enhanced fluorescence Plasmonics Super-resolution Surface enhanced raman scattering

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Published on: January 21, 2013

Area of Science:

Nanophotonics
Super-resolution microscopy
Plasmonics

Background:

Optical diffraction limits hinder visualization of fine biological structures.
Plasmonics, the interaction of light with metallic nanostructures, offers novel optical manipulation capabilities.

Purpose of the Study:

To review recent advancements in plasmonic-assisted super-resolution microscopy.
To highlight the role of plasmonic nanostructures in overcoming the diffraction limit.

Main Methods:

Survey of plasmonic-assisted super-resolution microscopy techniques.
Discussion of plasmonic nanoprobes, including surface-enhanced Raman scattering (SERS) and plasmon-enhanced fluorescence nanoparticles.
Analysis of electromagnetic field enhancement near metallic nanostructures.

Main Results:

Plasmonic field enhancement provides a method to manipulate illumination for super-resolution.
Plasmonic nanoprobes serve as effective contrast agents in super-resolution imaging.
Significant progress has been made in plasmonic-assisted super-resolution microscopy.

Conclusions:

Plasmonics is crucial for advancing super-resolution microscopy.
Plasmonic nanoprobes offer unique advantages for biological imaging.
Future developments promise expanded biological applications.