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Related Concept Videos

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The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
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Tooth Anatomy01:21

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The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
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Nursing management for a patient with arteriosclerosis involves a comprehensive approach focusing on lifestyle modification, disease monitoring, education, and symptomatic care. Here is an overview of effective nursing strategies:Assessment and Monitoring: Initial and ongoing assessments are crucial. Nurses must document the patient's medical history, including any hypertension, diabetes, hyperlipidemia, and other cardiovascular diseases. Assessments also cover family history and lifestyle...
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Cardiac Output II: Effect of Stroke Volume on Cardiac Output01:22

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Cardiac output (CO), the amount of blood the heart pumps per minute, is a parameter in cardiovascular physiology determined by stroke volume and heart rate. Stroke volume, the amount of blood pushed from one of the ventricles per heartbeat, is influenced by preload, afterload, and contractility.
Preload
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Updated: Dec 14, 2025

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Association between Tooth Loss and Stroke: A Systematic Review.

Nathalia Carolina Fernandes Fagundes1, Roberta Souza D'Almeida Couto2, Ana Paula Taborda Brandão2

  • 1School of Dentistry, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
|July 22, 2020
PubMed
Summary

This review suggests a link between tooth loss and stroke risk. However, current evidence is limited, necessitating further research with robust study designs to confirm this association.

Keywords:
EdentulousMouthStrokeTooth loss

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Area of Science:

  • Oral Health
  • Neurology
  • Public Health

Background:

  • Tooth loss is a prevalent issue with potential systemic health implications.
  • Stroke is a leading cause of disability and mortality worldwide.
  • Understanding risk factors for stroke is crucial for prevention strategies.

Purpose of the Study:

  • To systematically review and evaluate the association between tooth loss and stroke.
  • To synthesize evidence from observational studies on this relationship.

Main Methods:

  • Systematic review adhering to Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines.
  • Searches conducted across major databases including PubMed, Scopus, Web of Science, The Cochrane Library, LILACS, and OpenGrey.
  • Included observational studies on adults comparing tooth loss (Exposition) with no tooth loss (Comparison) regarding stroke (Outcome).
  • Data extraction, quality assessment, risk of bias evaluation, and certainty of evidence assessment using the GRADE approach were performed.

Main Results:

  • A total of 925 studies were initially identified, with 9 observational studies included in the final review.
  • Seven of the included studies indicated a positive association between tooth loss and stroke.
  • All included studies exhibited a low risk of bias but presented a low certainty of evidence.

Conclusions:

  • A potential association between tooth loss and stroke is suggested by the current literature.
  • The low certainty of evidence, likely due to the observational nature of the studies, highlights the need for further investigation.
  • High-quality research with improved methodological design is required to definitively establish the relationship between tooth loss and stroke.