Related Experiment Video
Updated: Dec 14, 2025
An Immature Murine Model of Reversible Unilateral Ureteral Obstruction
Published on: April 4, 2025
Urolithiasis, growth and blood pressure in childhood: A case-control study
Mehraban Navaei1, Saeideh Vafa1, Zohreh Sajadi Hezaveh1
1Student Research Committee, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
Insights
Childhood kidney stones (urolithiasis) may slightly impact weight and BMI for age, but generally do not affect growth or blood pressure in children.
Area of Science:
- Pediatric Urology
- Nephrology
- Child Health
Background:
- Kidney stones (urolithiasis) pose serious health risks, particularly for children.
- Early-onset urolithiasis can lead to significant complications.
Purpose of the Study:
- To evaluate the impact of a history of kidney stones on children's current blood pressure.
- To assess the effect of kidney stone history on children's growth parameters.
Main Methods:
- A case-control study involving 200 children (100 with and 100 without a history of urolithiasis).
- Measurements included demographic data, height, weight, Body Mass Index (BMI), BMI for age, and blood pressure index.
- Data collected from Pediatric Urology clinics at Aliasghar Hospital, Tehran, Iran.
Main Results:
- Significant differences observed in birth type, infant feeding, and caloric intake between groups.
- Children with a history of kidney stones had lower current weight and BMI for age.
- No significant association found between kidney stone history and blood pressure or height.
Conclusions:
- Childhood urolithiasis does not significantly affect growth failure or blood pressure.
- A history of kidney stones may have a minor impact on weight and BMI for age in older children.
Background & Aims:
Kidney stone is a life-threatening disease with subsequent complications, especially in children who overtake this disease in early ages. This study assessed the effect of kidney stone history on current blood pressure and growth parameters of children.
Methods:
A two hundred children with (n = 100) and without (n = 100) a history of urolithiasis from Pediatric Urology clinics at the Aliasghar hospital, Tehran, Iran, participated in this case-control study. Several demographic data, height, weight, body mass index (BMI), BMI for age and blood pressure index were measured as the primary outcomes.
Results:
type of birth and infancy feeding, carbohydrate and energy intake were significantly different between the two groups (P = 0.008, 0.002, 0.03 and < 0.001 respectively). Ordinal logistic regression analysis showed that the current weight (P = 0.001) and BMI for age (P = 0.02) of the stone formers were lower than the non-stone formers, while no significant association found between the blood pressure or current height and the history of urolithiasis.
Conclusion:
Our findings suggest that childhood urolithiasis has no significant effect on growth failure and blood pressure in childhood but it has a little impact on weight and BMI for age in older ages.
Related Concept Videos
01:27Urinary Tract Calculi IV: Nutrition Therapy and Prevention
01:28Urinary Tract Calculi I: Introduction
01:30Urinary Tract Calculi III: Medical Management
01:26Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
01:28Urinary Tract Calculi V: Nursing Management
01:18Hypertension and Regulation of Blood Pressure