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Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
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Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
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Automated Analysis of C. elegans Swim Behavior Using CeleST Software
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Geriatric Invertebrates.

Sarah Pellett1, Michelle O'Brien2, Benjamin Kennedy3

  • 1Animates Veterinary Clinic, 2 The Green, Thurlby, Lincolnshire PE10 0EB, UK.

The Veterinary Clinics of North America. Exotic Animal Practice
|July 22, 2020
PubMed
Summary
This summary is machine-generated.

Caring for aging invertebrates requires attention to their welfare. Veterinary intervention, supportive care, and euthanasia are options for managing age-related conditions in these popular pets.

Keywords:
AgingArthropodDiseaseInvertebrateMollusk

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Area of Science:

  • Veterinary medicine
  • Zoology
  • Animal welfare science

Background:

  • Invertebrates are increasingly popular as pets.
  • Aging invertebrate collections necessitate veterinary consideration.
  • Animal welfare is paramount when addressing invertebrate health issues.

Purpose of the Study:

  • To discuss aging in various invertebrate species.
  • To focus on species commonly encountered in general veterinary practice.
  • To outline considerations for veterinary intervention in aging invertebrates.

Main Methods:

  • Review of aging processes across diverse invertebrate taxa.
  • Focus on clinical presentation and management of age-related conditions.
  • Discussion of supportive care and euthanasia protocols.

Main Results:

  • Aging affects numerous invertebrate species, presenting unique challenges.
  • General practice veterinarians may encounter aging invertebrates requiring specialized care.
  • Supportive care can extend lifespan, but euthanasia is sometimes necessary.

Conclusions:

  • Veterinary professionals must be prepared to manage aging invertebrates.
  • Consideration of animal welfare is crucial throughout the process.
  • Euthanasia should be considered for invertebrates with unmanageable age-related conditions.